Families and caregivers should be advised of the need for close observation and communication with the prescriber. Monitor patients closely for clinical worsening, suicidality, or unusual changes in behavior. This risk must be balanced with the clinical need. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults older than 24 years, and there was a reduction in risk with antidepressants compared with placebo in adults aged 65 or older. Oral route (Tablet Tablet, Extended Release)Īntidepressants increased the risk of suicidal thinking and behavior in children, adolescents, and young adults in short-term studies with major depressive disorder (MDD) and other psychiatric disorders. Venlafaxine is not approved for use in pediatric patients. In patients of all ages who are started on antidepressant therapy monitor closely for clinical worsening and emergence of suicidal thoughts and behaviors. These studies did not show an increase in the risk of suicidal thoughts and behavior with antidepressant use in patients older than 24 years there was a reduction in risk with antidepressant use in patients aged 65 or older.
Antidepressants increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in short-term studies.
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